Journal article
Electron Microscopic Study of Corneal Epithelial-Endothelial Interactions in Organ Culture
Ophthalmology (Rochester, Minn.), v 91(6), pp 553-557
Jun 1984
PMID: 6462620
Abstract
The interactions between rabbit corneal epithelium and endothelium were investigated in an organ culture model using scanning electron microscopy and correlative light microscopy. Following mechanical removal of corneal endothelium, corneal epithelium was observed to migrate across the cut surface of the corneal stroma and onto the denuded Descemet's membrane after 48 hours in organ culture. By 72 hours, a distinct line of contact between the migrated epithelium and endothelium was established. Following epithelialendothelial contact, no cellular migration occurred. Corneal endothelial inhibition of epithelial migration may be a major factor in the prevention of surface epithelial invasion and proliferation following surgery and trauma.
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Details
- Title
- Electron Microscopic Study of Corneal Epithelial-Endothelial Interactions in Organ Culture
- Creators
- Joseph W. Sassani - Penn Presbyterian Medical CenterThomas John - Hospital of the University of PennsylvaniaJ. Douglas Cameron - Penn Presbyterian Medical CenterMyron Yanoff - Hospital of the University of PennsylvaniaRalph C. Eagle - Hospital of the University of Pennsylvania
- Publication Details
- Ophthalmology (Rochester, Minn.), v 91(6), pp 553-557
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Ophthalmology [Historical]
- Web of Science ID
- WOS:A1984SY31400004
- Scopus ID
- 2-s2.0-0021192158
- Other Identifier
- 991020836448904721
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Ophthalmology