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Electrophysiological Recordings in Pallidotomy Localized to 3D Stereoscopic Imaging
Journal article   Peer reviewed

Electrophysiological Recordings in Pallidotomy Localized to 3D Stereoscopic Imaging

Richard M Lehman, Evangelia Micheli-Tzanakou, Jian Zheng and Jennifer L Hamilton
Stereotactic and functional neurosurgery, v 72(2-4)
01 Jan 1999
PMID: 10853076

Abstract

Movement Disorders
A quantitative on-line analysis of electrical activity in the pallidum of Parkinsonian patients has been developed to determine the focal point of lesioning. A 3D volume image system has been developed to display basal ganglia anatomy and coregister the electrophysiological data within the globus pallidus. Thirty patients undergoing 41 pallidotomies are presented. Neuronal activity from the pallidum is recorded using a semi-microelectrode. Based on this activity, lesioning is performed. Postlesion recordings are made to determine the necessity of additional lesioning. A stereoscopic 3D volume MR image system has been developed that along with on-line signal processing allows visualization of high neural activity in the pallidum and postlesion residual activity.

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Web of Science research areas
Neuroimaging
Neurosciences
Surgery
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