Journal article
Elevated Platelet MAO is Related to Impulsivity in Disruptive Behavior Disorders
Journal of the American Academy of Child and Adolescent Psychiatry, v 28(5), pp 754-760
1989
PMID: 2793804
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Platelet monoamine oxidase (MAO) activity was measured in 32 drug-free prepubertal boys with externalizing symptoms of disruptive behavior disorders and 47 boys with no
DSM-III-R diagnoses, and correlated to questionnaire and laboratory performance measures of impulsivity. A subgroup of boys with high MAO activity exhibited significantly poorer performance (i.e., more impulsivity) than a subgroup of low MAO activity on laboratory tasks requiring response inhibition. High MAO patients were more impulsive than high MAO controls on some performance tasks and elevated platelet MAO was unrelated to personality questionnaire measures of impulsivity or to patient status. These data suggest that biological markers such as MAO activity may correlate better with performance than clinical questionnaire measures. Abnormally high platelet MAO activity may not be sufficient to produce externalizing symptoms in children, perhaps interacting with an underlying behavioral dimension of impulsivity.
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Details
- Title
- Elevated Platelet MAO is Related to Impulsivity in Disruptive Behavior Disorders
- Creators
- DAVID M. Stoff - York College of PennsylvaniaEITAN Friedman - York College of PennsylvaniaLEAFY Pollock - York College of PennsylvaniaBENEDETTO Vitiello - York College of PennsylvaniaPHILIP C. Kendall - York College of PennsylvaniaWAGNER H. Bridger - York College of PennsylvaniaLinda R Pollock - Communication
- Publication Details
- Journal of the American Academy of Child and Adolescent Psychiatry, v 28(5), pp 754-760
- Publisher
- Elsevier
- Grant note
- Grant #MH40364 / NIMH Award No. MH00590 / NIMH
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Communication
- Web of Science ID
- WOS:A1989AT65800018
- Scopus ID
- 2-s2.0-0024466316
- Other Identifier
- 991019183930604721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Pediatrics
- Psychiatry
- Psychology, Developmental