Journal article
Elevated mean translesional pressure gradients and flow limitation in significant human coronary stenoses before angioplasty
ASME BIOENG DIV PUBL BED, Vol.43, pp.63-64
01 Jan 1999
Abstract
Blood flow was simulated in patients (Wilson et al. 1988) with physiologically significant coronary lesions (minimal lesion size d sub(m) identical with 0.95 mm; 68% mean diameter stenosis; measured coronary flow reserve (CFR) of 2.3) by using computational hemodynamics. Computed mean pressure gradients were about 9 mm Hg for basal flow, and flow limiting values about approx. 35 mm Hg. Mean hyperemic flow rates were about 115 ml/min, and distal mean coronary pressures approx. 55 mm Hg, a level known to cause ischemia in the subendocardium (Brown et al. 1984), and consistent with the occurrence of angina in the patients.
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Details
- Title
- Elevated mean translesional pressure gradients and flow limitation in significant human coronary stenoses before angioplasty
- Creators
- Rupak BanerjeeMartin BackLloyd BackYoung Cho
- Publication Details
- ASME BIOENG DIV PUBL BED, Vol.43, pp.63-64
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Mechanical Engineering and Mechanics
- Identifiers
- 991019174028204721