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Endothelial shear stress and blood viscosity in peripheral arterial disease
Journal article   Peer reviewed

Endothelial shear stress and blood viscosity in peripheral arterial disease

Young I Cho, Daniel J Cho and Robert S Rosenson
Current atherosclerosis reports, v 16(4), pp 404-404
Apr 2014
PMID: 24519415

Abstract

Blood Viscosity - physiology Endothelial Cells - physiology Hemodynamics - physiology Humans Peripheral Arterial Disease - physiopathology Stress, Physiological Vascular Resistance - physiology
This review examines the emerging role of endothelial shear stress (ESS) and blood viscosity on the initiation and progression of atherosclerosis in peripheral arterial disease. Among the variables determining ESS, blood viscosity has to date been the most overlooked by clinical researchers. Blood viscosity is a laboratory assessment that is minimally invasive and modifiable using pharmacologic therapy as well as by hemodilution. Monitoring and controlling blood viscosity not only modulates ESS, but also reduces peripheral vascular resistance and increases blood flow to the lower extremities.

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Collaboration types
Domestic collaboration
Web of Science research areas
Peripheral Vascular Disease
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