Journal article
Endotracheal epinephrine in a canine anaphylactic shock model
Journal of the American College of Emergency Physicians, v 8(12), pp 500-503
Dec 1979
PMID: 513403
Abstract
This study was undertaken to determine if epinephrine administered endotracheally is as effective in treating anaphylactic shock as is intravenously administered epinephrine. An animal model of anaphylactic shock was produced in anesthetized dogs by the intravenous administration of histamine phosphate. Both the endotracheal and intravenous routes of epinephrine administration resulted in efficient and effective reversal of histamine-induced hypotension. At the doses employed, the intravenous administration of epinephrine resulted in the production of significantly (p < 0.05) greater numbers of ventricular cardiac arrhythmias than did the endotracheal route of administration.
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Details
- Title
- Endotracheal epinephrine in a canine anaphylactic shock model
- Creators
- Michael I. Greenberg - Drexel UniversityJames R. Roberts - Drexel UniversityJohn C. Krusz - Drexel UniversitySteven I. Baskin - Drexel University
- Publication Details
- Journal of the American College of Emergency Physicians, v 8(12), pp 500-503
- Publisher
- Elsevier
- Number of pages
- 4
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Emergency Medicine
- Web of Science ID
- WOS:A1979HW08800001
- Scopus ID
- 2-s2.0-0018580779
- Other Identifier
- 991021903267304721