Journal article
Endovascular treatment of acute ischemic stroke: the end or just the beginning?
Neurosurgical focus, v 36(1), pp 1-10
01 Jan 2014
PMID: 24380482
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Various endovascular intraarterial approaches are available for treating patients with acute ischemic stroke who present with severe neurological deficits. Three recent randomized trials-Interventional Management of Stroke (IMS) III, Mechanical Retrieval and Recanalization of Stroke Clots Using Embolectomy (MR RESCUE), and Synthesis Expansion: A Randomized Controlled Trial on Intra-Arterial Versus Intravenous Thrombolysis in Acute Ischemic Stroke (SYNTHESIS Expansion)-evaluated the efficacy of endovascular treatment of acute ischemic stroke and, after failing to demonstrate any significant clinical benefit of endovascular therapies, raised concerns and questions in the medical community regarding the future of endovascular treatment for acute ischemic stroke. In this paper, the authors review the evolution of endovascular treatment strategies for the treatment of acute stroke and provide their interpretation of findings and potential limitations of the three recently published randomized trials. The authors discuss the advantage of stent-retriever technology over earlier endovascular approaches and review the current status and future directions of endovascular acute stroke studies based on lessons learned from previous trials.
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Details
- Title
- Endovascular treatment of acute ischemic stroke: the end or just the beginning?
- Creators
- Maxim Mokin - University at Buffalo, State University of New YorkAlexander A. Khalessi - University of California, San DiegoJ. Mocco - Vanderbilt UniversityGiusepp E. Lanzino - Vanderbilt UniversityTravis M. Dumont - University at Buffalo, State University of New YorkRicardo A. Hanel - Jacksonville CollegeDemetrius K. Lopes - Rush University Medical CenterRichard D. Fessler - AscensionAndrew J. Ringer - Mayfield Brain & SpineBernard R. Bendok - Northwestern UniversityErol Veznedaroglu - Capital HealthAdnan H. Siddiqui - University at Buffalo, State University of New YorkL. Nelson Hopkins - University at Buffalo, State University of New YorkElad I. Levy - University at Buffalo, State University of New York
- Publication Details
- Neurosurgical focus, v 36(1), pp 1-10
- Publisher
- Amer Assoc Neurological Surgeons
- Number of pages
- 10
- Grant note
- Toshiba Boston Scientific ev3/Covidien Vascular Therapies 1R01NS064592-01A1 / NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA Erika Keeney foundation Codman & Shurtleff, Inc. University at Buffalo Abbott Vascular; Abbott Laboratories Stryker Covidien/ev3
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Neurosurgery
- Web of Science ID
- WOS:000329171100006
- Scopus ID
- 2-s2.0-84891927219
- Other Identifier
- 991021962291004721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Clinical Neurology
- Surgery