Journal article
Energy transduction catalysis by Escherichia coli DNA photolyase
Biochemistry (Easton), Vol.31(31), p7134
11 Aug 1992
Abstract
Escherichia coli photolyase is responsible for the repair of pyrimidine dimers during exposure of the enzyme-dimer complex to visible light after binding in a dark reaction. The energy transfer in the light reaction initiates the repair mechanism. Light can directly activate the coenzyme 1,5-dihydro flavin adenine dinucleotide (FADH2) or excite a pterin cofactor. The pterin cofactor then transfers the energy to FADH2. Replacing the natural pterin cofactor with a folate derivative reduced the quantum yield owing to the lower energy transfer efficiency of the replacement cofactor.
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Details
- Title
- Energy transduction catalysis by Escherichia coli DNA photolyase
- Creators
- Andrew J RamseyJames L AlderferMarilyn Schuman Jorns
- Publication Details
- Biochemistry (Easton), Vol.31(31), p7134
- Publisher
- American Chemical Society
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Biochemistry and Molecular Biology; [Retired Faculty]
- Identifiers
- 991020545238904721