Logo image
Enhanced Sampling in Molecular Dynamics Using Metadynamics, Replica-Exchange, and Temperature-Acceleration
Journal article   Open access   Peer reviewed

Enhanced Sampling in Molecular Dynamics Using Metadynamics, Replica-Exchange, and Temperature-Acceleration

Cameron Abrams and Giovanni Bussi
Entropy (Basel, Switzerland), v 16(1), pp 163-199
02 Jan 2014
url
https://doi.org/10.3390/e16010163View
Published, Version of Record (VoR) Open

Abstract

C. Abrams and G. Bussi, Entropy 16, 163 (2014) We review a selection of methods for performing enhanced sampling in molecular dynamics simulations. We consider methods based on collective variable biasing and on tempering, and offer both historical and contemporary perspectives. In collective-variable biasing, we first discuss methods stemming from thermodynamic integration that use mean force biasing, including the adaptive biasing force algorithm and temperature acceleration. We then turn to methods that use bias potentials, including umbrella sampling and metadynamics. We next consider parallel tempering and replica-exchange methods. We conclude with a brief presentation of some combination methods.

Metrics

10 Record Views
372 citations in Scopus
659 readers on Mendeley
5 readers on CiteULike

Details

UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

InCites Highlights

Data related to this publication, from InCites Benchmarking & Analytics tool:

Collaboration types
Domestic collaboration
International collaboration
Web of Science research areas
Physics, Multidisciplinary
Logo image