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Enhanced antimicrobial effect of ultrasound by the food colorant Erythrosin B
Journal article   Open access   Peer reviewed

Enhanced antimicrobial effect of ultrasound by the food colorant Erythrosin B

Luis J. Bastarrachea, Martin Walsh, Steven P. Wrenn and Rohan V. Tikekar
Food research international, v 100(Pt 1), pp 344-351
01 Oct 2017
PMID: 28873696
url
https://doi.org/10.1016/j.foodres.2017.07.012View
Accepted (AM)Open Access (Publisher-Specific) Open

Abstract

Food Science & Technology Life Sciences & Biomedicine Science & Technology
The synergistic combination of the food colorant Erythrosin B (E-B, FD & C 3) (0, 25, and 50 mu M) and low-frequency ultrasound (20 kHz, 0.86-0.90 W mL(-1)) was evaluated against Listeria innocua. Although E-B was antibacterial by itself, the inactivation rate significantly increased in a concentration-dependent manner upon exposure to ultrasound and followed a sigmoidal behavior. The enhanced antimicrobial effect of E-B in the presence of ultrasound can be explained in part from a microbubble disappearance study in which it was confirmed that the presence of E-B enhances inertial cavitation, thereby enhancing the antimicrobial effect of ultrasound. The inactivation rate in a sequential treatment, where L. innocua was sonicated for 4 min followed by exposure to 25 mu M Erythrosin B, was comparable to that obtained by the simultaneous treatment, indicating complementary mechanisms of inactivation. Fluorescence microscopy showed attachment of E-B to the cells, which may explain its intrinsic antimicrobial property. Other mechanism may include the confirmed decrease in the cavitation threshold of water by addition of E-B, resulting in more effective cavitation. The study offers a proof-of-concept of a novel approach to complement ultrasound treatment for enhanced microbial inactivation.

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Collaboration types
Domestic collaboration
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Food Science & Technology
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