Journal article
Enhancement of Hypoxemia by Atrial Shunting in Cystic Fibrosis
Chest, v 98(3), pp 543-545
Sep 1990
PMID: 2394134
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Patients with CF may develop hypoxemia which seems disproportionate to the degree of pulmonary disease. In a series of patients with CF and advanced pulmonary disease undergoing transesophageal echocardiography for the evaluation of cor pulmonale, eight of 15 patients were found to have atrial shunts through a stretched foramen ovale. To our knowledge, this is the first observation of intracardiac shunting in CF. This phenomenon may account for unexplained levels of cyanosis and worsening of hypoxemia with exercise, vasodilators, or PEEP and poses the threat of paradoxic emboli when central venous lines are used in these patients.
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Details
- Title
- Enhancement of Hypoxemia by Atrial Shunting in Cystic Fibrosis
- Creators
- Alexander Davidson - Hahnemann University HospitalKrishnaswany Chandrasekaran - Hahnemann University HospitalLouis Guida - Hahnemann University HospitalDouglas S. Holsclaw - Hahnemann University Hospital
- Publication Details
- Chest, v 98(3), pp 543-545
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Web of Science ID
- WOS:A1990DX28400008
- Scopus ID
- 2-s2.0-0025147591
- Other Identifier
- 991019353720104721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Critical Care Medicine
- Respiratory System