Journal article
Enterobacter Endocarditis
Scandinavian journal of infectious diseases, v 24(2), pp 233-240
1992
PMID: 1641601
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Endocarditis due to Enterobacter species is very rare. We recently cared for a patient who developed E. cloacae endocarditis following mitral valve replacement with a porcine heterograft, and was successfully treated with antibiotic therapy alone. A review of the literature disclosed an additional 17 well-described cases of enterobacter endocarditis. Two-thirds of the patients had underlying cardiac disease. The mitral valve was most frequently involved (10/16 cases) with 4 of the patients having concomitant aortic valve involvement. The overall mortality rate was 44.4%. Antibiotic therapy of enterobacter endocarditis should consist of the combination of a beta-lactam antibiotic and an aminoglycoside with careful monitoring of blood cultures to assure the adequacy of therapy. Resistance of enterobacter to previously susceptible antibiotics may occur during therapy due to induction of a chromosomally mediated beta-lactamase, necessitating a change in antimicrobial therapy. Valvular surgery is indicated for patients failing medical management
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Details
- Title
- Enterobacter Endocarditis
- Creators
- Allan R. Tunkel - 1From the Division of Infectious Diseases and Department of Internal Medicine, Medical College of Pennsylvania, Philadelphia, PennsylvaniaMichael J. Fisch - 1From the Division of Infectious Diseases and Department of Internal Medicine, Medical College of Pennsylvania, Philadelphia, PennsylvaniaAndrew Schlein - 1From the Division of Infectious Diseases and Department of Internal Medicine, Medical College of Pennsylvania, Philadelphia, PennsylvaniaW. Michael Scheld - 1From the Division of Infectious Diseases and Department of Internal Medicine, Medical College of Pennsylvania, Philadelphia, Pennsylvania
- Publication Details
- Scandinavian journal of infectious diseases, v 24(2), pp 233-240
- Publisher
- Informa UK Ltd
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Medical College of Pennsylvania and Hahnemann University (1993-1996, 1998-2002)
- Web of Science ID
- WOS:A1992HZ29800017
- Scopus ID
- 2-s2.0-0026747152
- Other Identifier
- 991019346796704721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Infectious Diseases