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Journal article
Eosinophilic Myenteric Ganglionitis Presenting as Sigmoid Volvulus: A Brief Report
The American surgeon, Vol.89(11), pp.5021-5023
01 Nov 2023
PMID: 37501639
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Eosinophilic myenteric ganglionitis (EMG) is a rare pathologic finding within the Auerbach myenteric plexus characterized by eosinophilic infiltration on light microscopy. The plexus’s ultimate obliteration results in chronic intestinal pseudo-obstruction (CIPO). EMG is almost exclusively seen in the pediatric population. The diagnosis of EMG is made through full-thickness rectal biopsy and EMG is not detectable through routine screening measures such as imaging or colonoscopy. The current treatment modality for this disorder is not standardized, and has often been treated with systemic steroids given its eosinophilic involvement. This case presents a 73-year-old male with chronic constipation presenting with new obstipation in the setting of recent orthopedic intervention requiring outpatient opioids. Admission radiographs were consistent with sigmoid volvulus. Following endoscopic detorsion, exploratory laparotomy revealed diffuse colonic dilation and distal ischemia requiring a Hartmann’s procedure. Surgical pathology revealed EMG, increasing the complexity of subsequent surgical decision-making after his urgent operation.
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Details
- Title
- Eosinophilic Myenteric Ganglionitis Presenting as Sigmoid Volvulus: A Brief Report
- Creators
- Alyson Kim - Department of Pathology and Laboratory MedicineJeffrey L. Roberson - University of PennsylvaniaLillias H. Maguire - Hospital of the University of PennsylvaniaBo Jian - Hospital of the University of PennsylvaniaNicole M. Saur - Hospital of the University of Pennsylvania
- Publication Details
- The American surgeon, Vol.89(11), pp.5021-5023
- Publisher
- SAGE Publications
- Number of pages
- 3
- Grant note
- 1K08DK124687 / National Institute of Diabetes and Digestive and Kidney Diseases (https://doi.org/10.13039/100000062) Measey Foundation
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- College of Medicine
- Web of Science ID
- WOS:001038721100001
- Scopus ID
- 2-s2.0-85165955343
- Other Identifier
- 991021860725304721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Surgery