Journal article
Epidemiology of Invasive Fungal Disease in Pediatric Heart Transplant Recipients
Journal of the Pediatric Infectious Diseases Society, v 15(1), 101
17 Jan 2026
PMID: 41206107
Abstract
We describe the epidemiology of invasive fungal disease (IFD) in pediatric heart transplant recipients. Eight patients (4%) suffered IFD. Prolonged central access, delayed chest closure, broad-spectrum antibiotics, and extracorporeal membrane oxygenation (ECMO) were associated with early post-transplant IFD. Delayed chest closure and ECMO were associated with administration of systemic antifungals.
Invasive fungal disease in pediatric heart transplant recipients is rare but associated with significant mortality. Possible associations between surgical and medical complexity and the onset of fungal disease warrant further investigation with large-scale, multi-center studies.
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Details
- Title
- Epidemiology of Invasive Fungal Disease in Pediatric Heart Transplant Recipients
- Creators
- Matthew Liversedge - Cincinnati Children's Hospital Medical CenterJeffrey Wang - Drexel UniversityMickael Boustany - Children's Hospital of PhiladelphiaAnna Sharova - Children's Hospital of PhiladelphiaKimberly Y. Lin - Children's Hospital of PhiladelphiaMatthew J. O'Connor - Childrens Hosp Philadelphia, Div Cardiol, Philadelphia, PA USALara Danziger-Isakov - Cincinnati Children's Hospital Medical CenterThomas D. Ryan - Cincinnati Children's Hospital Medical CenterKevin J. Downes - University of PennsylvaniaWilliam R. Otto - Cincinnati Children's Hospital Medical Center
- Publication Details
- Journal of the Pediatric Infectious Diseases Society, v 15(1), 101
- Publisher
- Oxford University Press
- Number of pages
- 6
- Grant note
- Pediatric Infectious Disease Society's Summer Research Award Infectious Diseases Society of America's Grants for Emerging Researchers/Clinicians Mentorship
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- College of Medicine
- Web of Science ID
- WOS:001674629400001
- Scopus ID
- 2-s2.0-105029066597
- Other Identifier
- 991022197017404721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Infectious Diseases
- Pediatrics