Journal article
Estimation of Stressed Blood Volume in Patients With Cardiogenic Shock From Acute Myocardial Infarction and Decompensated Heart Failure
Journal of cardiac failure, v 27(10), pp 1141-1145
01 Oct 2021
PMID: 33862252
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Sympathetically mediated redistribution of blood from the unstressed venous reservoir to the hemodynamically active stressed compartment is thought to contribute to congestion in cardiogenic shock (CS). We used a novel computational method to estimate stressed blood volume (SBV) in CS and assess its relationship with clinical outcomes.
Hemodynamic parameters including estimated SBV (eSBV) were compared among patients from the Cardiogenic Shock Working Group registry with a complete set of hemodynamic data. eSBV was compared across shock etiologies (acute myocardial infarction and CS (AMI-CS) vs heart failure with CS (HF-CS), Society for Cardiovascular Angiography and Interventions stage, and between survivors and nonsurvivors. Among 528 patients with patients analyzed, the mean eSBV was 2423 mL/70 kg and increased with increasing Society for Cardiovascular Angiography and Interventions stage (B, 2029 mL/70 kg; C, 2305 mL/70 kg; D, 2496 mL/70 kg; E, 2707 mL/70 kg; P < .001). The eSBV was significantly greater among patients with HF-CS who died compared with survivors (2733 vs 2357 mL/70 kg; P < .001), whereas no significant difference was observed between outcome groups in AMI-CS (2501 mL/70 kg vs 2384 mL/70 kg; P = .19).
eSBV is a novel integrated index of congestion which correlates with shock severity. eSBV was higher in patients with HF-CS who died; no difference was observed in patients with AMI-CS, suggesting that congestion may play a more significant role in the deterioration of patients with HF-CS
Metrics
Details
- Title
- Estimation of Stressed Blood Volume in Patients With Cardiogenic Shock From Acute Myocardial Infarction and Decompensated Heart Failure
- Creators
- Evan H. Whitehead - Massachusetts General HospitalKatherine L. Thayer - Tufts Medical CenterKenji Sunagawa - Circulatory System Research Foundation, Tokyo, JapanJaime Hernandez-Montfort - Cleveland Clinic FloridaA. Reshad Garan - Beth Israel Deaconess Medical CenterManreet K. Kanwar - Allegheny Health NetworkShashank S. Sinha - Alaska Heart and Vascular InstituteClaudius Mahr - University of WashingtonNavin K Kapur - Tufts Medical CenterDaniel Burkhoff - Cardiovascular Research Foundation
- Publication Details
- Journal of cardiac failure, v 27(10), pp 1141-1145
- Publisher
- Elsevier
- Number of pages
- 5
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Cardiology
- Web of Science ID
- WOS:000709697700012
- Scopus ID
- 2-s2.0-85106258172
- Other Identifier
- 991021932192504721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Cardiac & Cardiovascular Systems