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Accepted (AM)Open Access (License Unspecified), Open
Journal article
Ethical considerations in global HIV phylogenetic research
The lancet HIV, v 5(11), pp E656-E666
01 Nov 2018
PMID: 30174214
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Phylogenetic analysis of pathogens is an increasingly powerful way to reduce the spread of epidemics, including HIV. As a result, phylogenetic approaches are becoming embedded in public health and research programmes, as well as outbreak responses, presenting unique ethical, legal, and social issues that are not adequately addressed by existing bioethics literature. We formed a multidisciplinary working group to explore the ethical issues arising from the design of, conduct in, and use of results from HIV phylogenetic studies, and to propose recommendations to minimise the associated risks to both individuals and groups. We identified eight key ethical domains, within which we highlighted factors that make HIV phylogenetic research unique. In this Review, we endeavoured to provide a framework to assist researchers, public health practitioners, and funding institutions to ensure that HIV phylogenetic studies are designed, done, and disseminated in an ethical manner. Our conclusions also have broader relevance for pathogen phylogenetics.
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Details
- Title
- Ethical considerations in global HIV phylogenetic research
- Creators
- Cordelia E. M. Coltart - UCL, Inst Global Hlth, London, EnglandAnne Hoppe - University College LondonMichael Parker - Wellcome Centre for Ethics and HumanitiesLiza Dawson - Office of AIDS ResearchJoseph J. Amon - Princeton UniversityMusonda Simwinga - University of ZambiaGail Geller - Johns Hopkins Berman Institute of BioethicsGail Henderson - University of North Carolina at Chapel HillOliver Laeyendecker - National Institutes of HealthJoseph D. Tucker - University of North Carolina at Chapel HillPatrick Eba - International Social Security AssociationVladimir Novitsky - Harvard UniversityAnne-Mieke Vandamme - KU LeuvenJanet Seeley - London School of Hygiene & Tropical MedicineGina Dallabetta - Bill & Melinda Gates FoundationGuy Harling - University College LondonM. Kate Grabowski - Rakai Health Sciences ProgramPeter Godfrey-Faussett - Joint UN Programme HIV AIDS, Geneva, SwitzerlandChristophe Fraser - Open Data InstituteMyron S. Cohen - University of North Carolina at Chapel HillDeenan Pillay - Africa Health Research InstituteEthics HIV Phylogenetics Workin
- Publication Details
- The lancet HIV, v 5(11), pp E656-E666
- Publisher
- Elsevier
- Number of pages
- 11
- Grant note
- MR/R015600/1 / MRC; UK Research & Innovation (UKRI); Medical Research Council UK (MRC) PANGEA-HIV Steering Committee
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Community Health and Prevention
- Web of Science ID
- WOS:000449490500014
- Scopus ID
- 2-s2.0-85057172173
- Other Identifier
- 991021895803604721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Immunology
- Infectious Diseases