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Accepted (AM)Open Access (License Unspecified), Open
Journal article
Ethnic differences in ambient air pollution and risk of acute ischemic stroke
Environmental research, v 143(Pt A), pp 62-67
Nov 2015
PMID: 26451880
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
To investigate the association between short-term changes in ambient pollution (particulate matter <2.5μm in aerodynamic diameter (PM2.5) and ozone (O3)) and the risk of ischemic stroke among individuals living in a bi-ethnic community and whether this association is modified by ethnicity.
We identified incident ischemic stroke cases from the population-based Brain Attack Surveillance in Corpus Christi (BASIC) project between 2000 and 2012. Associations between PM2.5 (mean 24-h) and O3 (maximal 8-h) levels, measured on the same-day and lags of 1–3 days, and odds of ischemic stroke were assessed using a time-stratified case-crossover design and modeled using conditional logistic regression. We explored race/ethnicity (Mexican American versus non-Hispanic white) as a modifier by including interaction terms in the models.
There were 2948 ischemic strokes with median age 71 years (IQR: 59-80). We observed no overall associations between the air pollutants and odds of ischemic stroke at any lag. When stratified by ethnicity, higher O3 was consistently associated with greater odds of ischemic stroke for non-Hispanic whites, but not for Mexican Americans. Higher PM2.5 was generally associated with lower odds of ischemic stroke for non-Hispanic whites but modestly greater odds for Mexican Americans.
Ethnic differences in the associations between ischemic stroke and short-term exposures to O3 and PM2.5 were suggested indicating that further study in diverse populations may be warranted.
•First study to examine possible ethnic differences in air pollution on stroke risk.•Case-crossover design to assess associations between PM2.5/O3 and stroke incidence.•Suggestive association between PM2.5 and ischemic stroke among Mexican Americans.•Suggestive association between O3 and ischemic stroke among non-Hispanic whites.•Further study in diverse populations is warranted.
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Details
- Title
- Ethnic differences in ambient air pollution and risk of acute ischemic stroke
- Creators
- Jeffrey J. Wing - University of MichiganSara D. Adar - University of MichiganBrisa N. Sánchez - University of MichiganLewis B. Morgenstern - University of MichiganMelinda A. Smith - University of MichiganLynda D. Lisabeth - University of Michigan
- Publication Details
- Environmental research, v 143(Pt A), pp 62-67
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics
- Web of Science ID
- WOS:000365831400009
- Scopus ID
- 2-s2.0-84943402456
- Other Identifier
- 991020099924304721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Environmental Sciences
- Public, Environmental & Occupational Health