Journal article
Evaluation and Management of Biliary Dyskinesia in Children and Adolescents: A Systematic Review From the APSA Outcomes and Evidence-Based Committee
Journal of pediatric surgery, v 59(11), 161678
Nov 2024
PMID: 39227244
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The diagnosis and management of biliary dyskinesia in children and adolescents remains variable and controversial. The American Pediatric Surgical Association Outcomes and Evidence-Based Practice Committee (APSA OEBP) performed a systematic review of the literature to develop evidence-based recommendations.
Through an iterative process, the membership of the APSA OEBP developed five a priori questions focused on diagnostic criteria, indications for cholecystectomy, short and long-term outcomes, predictors of success/benefit, and outcomes of medical management. A systematic review was conducted, and articles were selected for review following Preferred Reporting Items for Systematic Review and Meta-analyses (PRISMA) guidelines. Risk of bias was assessed using Methodologic Index for Non-Randomized Studies (MINORS) criteria. The Oxford Levels of Evidence and Grades of Recommendation were utilized.
The diagnostic criteria for biliary dyskinesia in children and adolescents are not clearly defined. Cholecystectomy may provide long-term partial or complete relief in some patients; however, there are no reliable predictors of symptom relief. Some patients may experience resolution of symptoms with non-operative management.
Pediatric biliary dyskinesia remains an ill-defined clinical entity. Pediatric-specific guidelines are necessary to better characterize the condition, guide work-up, and provide management recommendations. Prospective studies are necessary to more reliably identify patients who may benefit from cholecystectomy.
Level 3-4.
Systematic Review of Level 3-4 Studies.
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Details
- Title
- Evaluation and Management of Biliary Dyskinesia in Children and Adolescents: A Systematic Review From the APSA Outcomes and Evidence-Based Committee
- Creators
- Afif N. Kulaylat - Penn State Milton S. Hershey Medical CenterDonald J. Lucas - Uniformed Services University of the Health SciencesHenry L. Chang - Johns Hopkins All Children's HospitalS. Christopher Derderian - Children's Hospital ColoradoAlana L. Beres - Drexel UniversityP. Benson Ham - Women & Children's Hospital of BuffaloCarlos T. Huerta - University of MiamiJason P. Sulkowski - Children's Hospital of Richmond at VCUDerek Wakeman - University of RochesterBrian R. Englum - University of Maryland, BaltimoreBrian C. Gulack - Rush University Medical CenterShannon N. Acker - University of Colorado DenverKatherine W. Gonzalez - St. Luke's Children's HospitalTamar L. Levene - Joe DiMaggio Children's HospitalEmily Christison-Lagay - Yale New Haven HospitalSara A. Mansfield - Nationwide Children's HospitalYasmine Yousef - Joe DiMaggio Children's HospitalChristopher P. Pennell - Mercy Medical CenterKatie W. Russell - University of UtahRebecca M. Rentea - University of Missouri–Kansas CityJun Tashiro - NYU Langone HealthDiana L. Diesen - The University of Texas Southwestern Medical CenterHanna Alemayehu - Emory UniversityRobert Ricca - University of South CarolinaLorraine Kelley-Quon - Children's Hospital of Los AngelesKristy L. Rialon - Baylor College of Medicine
- Publication Details
- Journal of pediatric surgery, v 59(11), 161678
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pediatrics; Surgery
- Web of Science ID
- WOS:001336494500001
- Scopus ID
- 2-s2.0-85202967193
- Other Identifier
- 991021969475004721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Pediatrics
- Surgery