Journal article
Evolution of radiotherapeutic techniques
Gynecologic oncology, v 2(2), pp 314-323
Aug 1974
PMID: 4457407
Abstract
Adenocarcinoma is the most common kind of tumor involving the uterine corpus, occurring in a frequency of 90% or better and found predominantly in postmenopausal women. Because of vaginal bleeding, diagnosis is made early and control rates are good. Regional lymph node metastases are found to occur in about 20% of all operable patients and more frequently in those with advanced lesions near the cervix.
Surgery alone fails not only because of metastases but also because of persistence in the vaginal vault and in the periurethral region. From a theoretical and practical viewpoint, preoperative irradiation is a valuable and important role in the treatment of carcinoma of the endometrium. Treatment calls for a technique that will effectively irradiate the uterine tissue, the vaginal vault, and the immediate extrauterine tissues in which postsurgical persistence is known to appear.
From the standpoint of survival, both preoperative external therapy and preoperative radium therapy are effective with equivalent survival figures. The incidence in our experience of vaginal recurrence in those patients who were irradiated preoperatively with external beam therapy techniques would indicate the need for supplemental radium within the vaginal vault.
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26 citations in Scopus
Details
- Title
- Evolution of radiotherapeutic techniques
- Creators
- Luther W. BradyGeorge C. LewisJohn AntoniadesSriprayoon PrasasvinichaiRichard J. TorpieSucha O. AsbellJohn R. GlassburnDavid SchatanoffThomas MacMurrayHahnemann Medical Coll. and Hospital, Philadelphia
- Publication Details
- Gynecologic oncology, v 2(2), pp 314-323
- Publisher
- Elsevier
- Number of pages
- 10
- Resource Type
- Journal article
- Language
- English
- Scopus ID
- 2-s2.0-0016202121
- Other Identifier
- 991021901309804721