Evolving Roles of Fluorodeoxyglucose and Sodium Fluoride in Assessment of Multiple Myeloma Patients Introducing a Novel Method of PET Quantification to Overcome Shortcomings of the Existing Approaches
Mahdi Zirakchian Zadeh, William Y. Raynor, Siavash Mehdizadeh Seraj, Cyrus Ayubcha, Esha Kothekar, Thomas Werner and Abass Alavi
Life Sciences & Biomedicine Radiology, Nuclear Medicine & Medical Imaging Science & Technology
PET with fluorodeoxyglucose and sodium fluoride (NaF) radiotracers has shown a great promise in assessing patients with multiple myeloma (MM). However, the standardization of PET/computed tomography scans interpretation in patients with myeloma in clinical practice is still debatable. This article reviews available data regarding the use of fluorodeoxyglucose and NaF PET in patients with MM. Introduced is a novel method of PET quantification as applied to patients with MM. A new concept for PET-based evaluation of patients with MM is also discussed: dual time point imaging. Finally, the role of NaF in assessment of cardiovascular complications of MM is described.
Evolving Roles of Fluorodeoxyglucose and Sodium Fluoride in Assessment of Multiple Myeloma Patients Introducing a Novel Method of PET Quantification to Overcome Shortcomings of the Existing Approaches
Creators
Mahdi Zirakchian Zadeh - Children's Hospital of Philadelphia
William Y. Raynor - Drexel University
Siavash Mehdizadeh Seraj - University of Pennsylvania
Cyrus Ayubcha - University of Pennsylvania
Esha Kothekar - University of Pennsylvania
Thomas Werner - University of Pennsylvania
Abass Alavi - University of Pennsylvania
Publication Details
PET clinics, v 14(3), pp 341-352
Publisher
Elsevier
Number of pages
13
Grant note
Region of Southern Denmark
University of Southern Denmark
Aase & Ejnar Danielsen Foundation
Family Hede Nielsen Foundation
Odense University Hospital
A.P. Moller Foundation (Fonden til laegevidenskabens fremme)
Harboe Foundation
Resource Type
Journal article
Language
English
Academic Unit
Radiology (Radiologic Sciences)
Web of Science ID
WOS:000467624300005
Scopus ID
2-s2.0-85064086751
Other Identifier
991019350589804721
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