Journal article
Expert Consensus on the Use of On-Demand Treatments for OFF Episodes in Parkinson's Disease: A Modified Delphi Panel
MOVEMENT DISORDERS CLINICAL PRACTICE, v 10(4), p652
Apr 2023
PMID: 37070052
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
BackgroundOn-demand treatments can treat OFF episodes in Parkinson's disease, however, there is limited information regarding when to prescribe them. ObjectiveDevelop expert consensus to determine appropriate clinical factors for considering on-demand treatments. MethodsUsing a RAND/UCLA modified Delphi panel method, a panel developed consensus on the use of on-demand treatments for OFF episodes. ResultsThe panel agreed on-demand treatments were appropriate when OFF episodes were associated with greater functional impact and interfered with basic daily activities. The panel also agreed on-demand treatment may be appropriate for patients with morning akinesia and/or delayed ON of first levodopa dose and >1 type of OFF episode (eg, early morning OFF or wearing OFF regardless of frequency). ConclusionsExperts agreed on-demand treatment is appropriate for many patients with OFF episodes. The greater the functional impact of OFF episodes, the more likely experts agreed that on-demand treatment is appropriate to prescribe.
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Details
- Title
- Expert Consensus on the Use of On-Demand Treatments for OFF Episodes in Parkinson's Disease: A Modified Delphi Panel
- Publication Details
- MOVEMENT DISORDERS CLINICAL PRACTICE, v 10(4), p652
- Publisher
- WILEY; HOBOKEN
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Drexel University
- Web of Science ID
- WOS:000946658600001
- Scopus ID
- 2-s2.0-85150623216
- Other Identifier
- 991021861175304721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Clinical Neurology