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Explant Analysis of Total Disc Replacement
Journal article   Open access   Peer reviewed

Explant Analysis of Total Disc Replacement

Paul A. Anderson, Steven M. Kurtz and Jeffrey M. Toth
Seminars in spine surgery, v 18(2), pp 109-116
2006
DOI: https://doi.org/10.1053/j.semss.2006.03.012
url
https://epublications.marquette.edu/cgi/viewcontent.cgi?article=1569&context=bioengin_facView
SubmittedOpen Access (License Unspecified),  Open

Abstract

bone in-growth explant analysis intervertebral disc arthroplasty wear
Explant analysis of human disc prostheses allow early evaluation of the host response to the prosthesis and the response of the prosthesis from the host. Furthermore, early predictions of failure and wear can be obtained. Thus far, about 2-3% of disc prostheses have been removed. Observed wear patterns are similar to that of appendicular prostheses including abrasions/scratching, burnishing, surface deformation, fatigue, and embedded debris. Chemically the polymeric components have shown little degradation in short-term implantation. In metal on metal prostheses the histologic responses consist of large numbers of metallic particles with occasional macrophages and giant cells. Only rare cases of significant inflammatory response from polymeric debris have been seen.

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