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Exposure Group Development in Support of the NIEHS GuLF Study
Journal article   Open access   Peer reviewed

Exposure Group Development in Support of the NIEHS GuLF Study

Mark R Stenzel, Caroline P Groth, Tran B Huynh, Gurumurthy Ramachandran, Sudipto Banerjee, Richard K Kwok, Lawrence S Engel, Aaron Blair, Dale P Sandler and Patricia A Stewart
Annals of work exposures and health, v 66(Suppl 1), pp i23-i55
07 Apr 2022
PMID: 35390128
url
https://academic.oup.com/annweh/article-pdf/66/Supplement_1/i23/43297004/wxab093.pdfView
Published, Version of Record (VoR) Open
url
https://doi.org/10.1093/annweh/wxab093View
Published, Version of Record (VoR) Open

Abstract

Disasters Humans Hydrocarbons National Institute of Environmental Health Sciences (U.S.) Occupational Exposure Petroleum Pollution - adverse effects United States
In the GuLF Study, a study investigating possible adverse health effects associated with work on the oil spill response and clean-up (OSRC) following the Deepwater Horizon disaster in the Gulf of Mexico, we used a job-exposure matrix (JEM) approach to estimate exposures. The JEM linked interview responses of study participants to measurement data through exposure groups (EGs). Here we describe a systematic process used to develop transparent and precise EGs that allowed characterization of exposure levels among the large number of OSRC activities performed across the Gulf of Mexico over time and space. EGs were identified by exposure determinants available to us in our measurement database, from a substantial body of other spill-related information, and from responses provided by study participants in a detailed interview. These determinants included: job/activity/task, vessel and type of vessel, weathering of the released oil, area of the Gulf of Mexico, Gulf coast state, and time period. Over 3000 EGs were developed for inhalation exposure and applied to each of 6 JEMs of oil-related substances (total hydrocarbons, benzene, toluene, ethylbenzene, total xylene, and n-hexane). Subsets of those EGs were used for characterization of exposures to dispersants, particulate matter, and oil mist. The EGs allowed assignment to study participants of exposure estimates developed from measurement data or from estimation models through linkage in the JEM for the investigation of exposure-response relationships.

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Collaboration types
Domestic collaboration
Web of Science research areas
Public, Environmental & Occupational Health
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