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Accepted (AM)Open Access (License Unspecified), Open
Journal article
Exposure to organophosphorus insecticides and increased risks of health and cancer in US women
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, v 80, 103474
Nov 2020
PMID: 32828957
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Results of this paper provide evidence that chronic long-term exposure to organophosphorus insecticides poses a significantly higher health risk for US women than for men, based on dialkylphosphate biomarker data from NHANES cycles 2003-2012. The risk of cardiovascular disease for female non-smokers aged 60-85 years in the highest dimethylthiophosphate (DMTP) urinary concentration quartile is 3.0 (odds ratio, OD = 3.0, 95%CI 1.4-6.4) times higher than that in the lowest quartile. Women with higher urinary DMTP concentrations also have significantly higher risk of asthma at the ages 6-39 years and an apparently higher risk of chronic bronchitis at the ages 60-85. Overall cancer risk is significantly higher for female non-smokers aged 60-85 years in the higher urinary DMTP quartiles (OD = 2.7, 95% CI 1.3-5.9). Increasing risks of breast cancer for female smokers and prostate cancer for male smokers aged 60-85 years with higher exposure to organophosphorus insecticides in the US are also significant.
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Details
- Title
- Exposure to organophosphorus insecticides and increased risks of health and cancer in US women
- Publication Details
- ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, v 80, 103474
- Publisher
- ELSEVIER; AMSTERDAM
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Drexel University
- Web of Science ID
- WOS:000583776900033
- Scopus ID
- 2-s2.0-85090552469
- Other Identifier
- 991021860770104721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Environmental Sciences
- Pharmacology & Pharmacy
- Toxicology