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Journal article
Exposure to volatile hydrocarbons and neurologic function among oil spill workers up to 6 years after the Deepwater Horizon disaster
Environmental research, 116069
04 May 2023
PMID: 37149022
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
During the 2010 Deepwater Horizon (DWH) disaster, oil spill response and cleanup (OSRC) workers were exposed to toxic volatile components of crude oil. Few studies have examined exposure to individual volatile hydrocarbon chemicals below occupational exposure limits in relation to neurologic function among OSRC workers.
To investigate the association of several spill-related chemicals (benzene, toluene, ethylbenzene, xylene, n-hexane, i.e., BTEX-H) and total petroleum hydrocarbons (THC) with neurologic function among DWH spill workers enrolled in the Gulf Long-term Follow-up Study.
Cumulative exposure to THC and BTEX-H across the oil spill cleanup period were estimated using a job-exposure matrix that linked air measurement data to detailed self-reported DWH OSRC work histories. We ascertained quantitative neurologic function data via a comprehensive test battery at a clinical examination that occurred 4-6 years after the DWH disaster. We used multivariable linear regression and modified Poisson regression to evaluate relationships of exposures (quartiles (Q)) with 4 neurologic function measures. We examined modification of the associations by age at enrollment (<50 vs. ≥50 years).
We did not find evidence of adverse neurologic effects from crude oil exposures among the overall study population. However, among workers ≥50 years of age, several individual chemical exposures were associated with poorer vibrotactile acuity of the great toe, with statistically significant effects observed in Q3 or Q4 of exposures (range of log mean difference in Q4 across exposures: 0.13-0.26 μm). We also observed suggestive adverse associations among those ≥ age 50 years for tests of postural stability and single-leg stance, although most effect estimates did not reach thresholds of statistical significance (p < 0.05).
Higher exposures to volatile components of crude oil were associated with modest deficits in neurologic function among OSRC workers who were age 50 years or older at study enrollment.
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Details
- Title
- Exposure to volatile hydrocarbons and neurologic function among oil spill workers up to 6 years after the Deepwater Horizon disaster
- Creators
- Dazhe Chen - University of North Carolina at Chapel HillEmily J Werder - National Institute of Environmental Health SciencesPatricia A Stewart - Stewart Exposure Assessments, LLC (United States, Arlington)Mark R Stenzel - Exposure Assessment Applications, LLC (United States, Arlington)Fredric E Gerr - University of IowaKaitlyn G Lawrence - National Institute of Environmental Health SciencesCaroline P Groth - West Virginia UniversityTran B Huynh - Drexel UniversityGurumurthy Ramachandran - Johns Hopkins UniversitySudipto Banerjee - University of California, Los AngelesW Braxton Jackson - Social & Scientific Systems, Inc (United States, Durham)Kate Christenbury - Social & Scientific Systems, Inc, a DLH Holdings Company, Durham, NC, USARichard K Kwok - National Institute on AgingDale P Sandler - National Institute of Environmental Health SciencesLawrence S Engel - University of North Carolina at Chapel Hill
- Publication Details
- Environmental research, 116069
- Publisher
- Elsevier
- Number of pages
- 11
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Environmental and Occupational Health
- Web of Science ID
- WOS:001002136100001
- Scopus ID
- 2-s2.0-85159561614
- Other Identifier
- 991020489106604721
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- Collaboration types
- Industry collaboration
- Domestic collaboration
- Web of Science research areas
- Environmental Sciences
- Public, Environmental & Occupational Health