Journal article
Expression of the SmB′ splicing protein in rodent cells capable of following an alternative RNA splicing pathway
FEBS letters, v 243(2)
30 Jan 1989
PMID: 2783916
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The expression of the SmB and SmB′ spliceosome proteins in a variety of cell types and tissues has been investigated. Although SmB is found in all cells studied, the SmB′ protein is found only in a small number of rodent cell types. The presence of this protein is correlated with the ability to utilize an alternative pathway of RNA splicing which is not available in most cell types. This is the first demonstration of tissue specific expression of a protein component of the spliceosome and suggests a role for SmB′ in the regulation of some cases of alternative RNA splicing.
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Details
- Title
- Expression of the SmB′ splicing protein in rodent cells capable of following an alternative RNA splicing pathway
- Creators
- Neil G. Sharpe - Middlesex HospitalDavid G. Williams - Kennedy CenterPamela Norton - Middlesex HospitalDavid S. Latchman - Middlesex Hospital
- Publication Details
- FEBS letters, v 243(2)
- Publisher
- Elsevier
- Number of pages
- 5
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Microbiology and Immunology
- Web of Science ID
- WOS:A1989T239900006
- Scopus ID
- 2-s2.0-0024509088
- Other Identifier
- 991020830153704721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Biochemistry & Molecular Biology
- Biophysics
- Cell Biology