Journal article
F-18-FDG PET/MRI Primary Staging of Cervical Cancer: A Pilot Study with PET/CT Comparison
Journal of nuclear medicine technology, v 48(4), pp 331-335
01 Dec 2020
PMID: 32709671
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
We report our PET/MRI experience from a pilot study that compared the diagnostic performance of F-18-FDG PET/MRI versus PET/CT in staging of cervical cancer. Methods: Six adults with newly diagnosed cervical cancer underwent a single F-18-FDG injection with a dual-imaging protocol: standard-ofcare PET/CT followed by research PET/MRI. The diagnostic interpretation and SUVmax for the 2 modalities were compared. Results: Both modalities detected all primary tumors (median size, 3.9 cm) and all 4 metastases present in 2 of the 6 patients (median size, 0.9 cm). PET/MRI provided greater diagnostic confidence than PET/CT and upstaged the disease in 4 patients. On the basis of the imaging findings alone, the additional information from PET/MRI would have led to a change in clinical management in 3 of 6 patients. The primary lesion showed a median SUV of 12.8 on PET/CT and 18.2 on PET/MRI (P = 0.03). SUVs, however, correlated strongly between the 2 modalities (rho = 0.96, P < 0.001). Conclusion: Our pilot study supports the notion that PET/MRI has the potential to impact clinical decisions and treatment strategies in women with cervical cancer. Further studies are, however, warranted to define the value that PET/MRI adds to PET/CT.
Metrics
Details
- Title
- F-18-FDG PET/MRI Primary Staging of Cervical Cancer: A Pilot Study with PET/CT Comparison
- Creators
- Nghi C. Nguyen - University of PittsburghSushil Beriwal - University of PittsburghChan-Hong Moon - University of PittsburghAlessandro Furlan - University of PittsburghJames M. Mountz - University of PittsburghBalasubramanya Rangaswamy - University of Pittsburgh
- Publication Details
- Journal of nuclear medicine technology, v 48(4), pp 331-335
- Publisher
- Soc Nuclear Medicine Inc
- Number of pages
- 5
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Radiation Oncology (and Nuclear Medicine)
- Web of Science ID
- WOS:000596227700008
- Scopus ID
- 2-s2.0-85097210948
- Other Identifier
- 991021897394104721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Radiology, Nuclear Medicine & Medical Imaging