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Journal article
Fabrication and magnetic control of alginate-based rolling microrobots
AIP advances, v 6(12), pp 125205-125205-7
01 Dec 2016
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Advances in microrobotics for biological applications are often limited due to their complex manufacturing processes, which often utilize cytotoxic materials, as well as limitations in the ability to manipulate these small devices wirelessly. In an effort to overcome these challenges, we investigated a facile method for generating biocompatible hydrogel based robots that are capable of being manipulated using an externally generated magnetic field. Here, we experimentally demonstrate the fabrication and autonomous control of loaded-alginate microspheres, which we term artificial cells. In order to generate these microparticles, we employed a centrifuge-based method in which microspheres were rapidly ejected from a nozzle tip. Specifically, we used two mixtures of sodium alginate; one containing iron oxide nanoparticles and the other containing mammalian cells. This mixture was loaded into a needle that was fixed on top of a microtube containing calcium chloride, and then briefly centrifuged to generate hundreds of Janus microspheres. The fabricated microparticles were then magnetically actuated with a rotating magnetic field, generated using electromagnetic coils, prompting the particles to roll across a glass substrate. Also, using vision-based feedback control, a single artificial cell was manipulated to autonomously move in a programmed pattern. (C) 2016 Author(s).
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Details
- Title
- Fabrication and magnetic control of alginate-based rolling microrobots
- Creators
- Jamel Ali - Drexel UniversityU. Kei Cheang - Drexel UniversityYigong Liu - Drexel UniversityHoyeon Kim - Southern Methodist Univ, Dept Mech Engn, Dallas, TX 75275 USALouis Rogowski - Southern Methodist UniversitySam Sheckman - Southern Methodist UniversityPrem Patel - Drexel UniversityWei Sun - Drexel UniversityMin Jun Kim - Southern Methodist University
- Publication Details
- AIP advances, v 6(12), pp 125205-125205-7
- Publisher
- American Institute of Physics
- Number of pages
- 7
- Grant note
- 32 CFR 168a / DoD, Air Force Office of Scientific Research, National Defense Science and Engineering Graduate (NDSEG) Fellowship IIS 1617949; CMMI 1634726 / National Science Foundation; National Science Foundation (NSF) 1712088 / Direct For Computer & Info Scie & Enginr; National Science Foundation (NSF); NSF - Directorate for Computer & Information Science & Engineering (CISE) 10052980 / Korea Evaluation Institute of Industrial Technology (KEIT) - Ministry of Trade, Industry, and Energy (MOTIE)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Mechanical Engineering and Mechanics
- Web of Science ID
- WOS:000392091500102
- Scopus ID
- 2-s2.0-85002949163
- Other Identifier
- 991019167812504721
UN Sustainable Development Goals (SDGs)
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Materials Science, Multidisciplinary
- Nanoscience & Nanotechnology
- Physics, Applied