Journal article
Failure to Replicate Evoked Potential Observations Suggesting Corpus Callosum Dysfunction in Schizophrenia
British journal of psychiatry, v 142(5), pp 471-476
May 1983
PMID: 6871561
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Somatosensory potentials (SEPs) evoked by vibrotactile finger stimulation have been reported to be the same in both hemispheres in schizophrenics, whereas they are asymmetrical in normals, with the contralateral hemisphere leading the ipsilateral (Jones and Miller, 1981). These findings were taken to indicate that the corpus callosum is nonfunctional in schizophrenics. To attempt replication of these results, vibrotactile SEPs of 6 schizophrenics and 6 normal controls were recorded with both bipolar and monopolar derivations. Assymetrical bipolar SEPs were obtained in both schizophrenics and controls; previous observations of schizophrenic-control differences were not replicated. Acceptable evidence of ipsilateral early SEPs was not obtained; the test procedure seems inappropriate for measuring callosal conduction time.
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Details
- Title
- Failure to Replicate Evoked Potential Observations Suggesting Corpus Callosum Dysfunction in Schizophrenia
- Creators
- Charles Shagass - Temple University Medical School and Eastern Pennsylvania Psychiatric Institute, Philadelphia PA 19129, U.S.ARichard C. Josiassen - Temple UniversityRichard A. Roemer - Temple University Medical School and Eastern Pennsylvania Psychiatric Institute, Philadelphia PA 19129, U.S.AJohn J. Straumanis - Temple University Medical School and Eastern Pennsylvania Psychiatric Institute, Philadelphia PA 19129, U.S.AStephen M. Slepner - Temple University Medical School and Eastern Pennsylvania Psychiatric Institute, Philadelphia PA 19129, U.S.A
- Publication Details
- British journal of psychiatry, v 142(5), pp 471-476
- Publisher
- Cambridge University Press
- Number of pages
- 6
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Psychiatry
- Web of Science ID
- WOS:A1983QX71500004
- Scopus ID
- 2-s2.0-0020532115
- Other Identifier
- 991019184312604721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Psychiatry