Journal article
Feasibility of breast radiation therapy in a Fanconi Anemia patient diagnosed with breast cancer: A case report and review of literature
Clinical and translational radiation oncology, v 28, pp 129-132
01 May 2021
PMID: 33981866
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
•We present the journey of an FA patient who developed metachronous bilateral breast cancers and was successfully treated with breast conserving therapy with no significant treatment related toxicity.
Fanconi Anemia (FA) is a rare inherited autosomal recessive disease that results in impaired double stranded DNA repair. This leads to both increased susceptibility to various cancers, as well as hypersensitivity to radiotherapy and systemic therapy; thus, increasing the complexity of oncological treatment paradigm.
Here, we present an FA patient who initially developed invasive breast cancer for which she received breast conserving treatment with no significant treatment related toxicity. This was followed by a diagnosis of high-grade ductal carcinoma-in-situ in the contralateral breast, which was managed successfully by surgery and meticulously planned adjuvant radiotherapy, with no treatment interruptions.
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Details
- Title
- Feasibility of breast radiation therapy in a Fanconi Anemia patient diagnosed with breast cancer: A case report and review of literature
- Creators
- Neha Hafeez - University of PittsburghHima Bindu Musunuru - UPMC Hillman Cancer CenterAndrew Keller - UPMC Hillman Cancer CenterSushil Beriwal - University of Pittsburgh
- Publication Details
- Clinical and translational radiation oncology, v 28, pp 129-132
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Radiation Oncology (and Nuclear Medicine)
- Web of Science ID
- WOS:000647678900019
- Scopus ID
- 2-s2.0-85104448550
- Other Identifier
- 991021897372004721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Oncology
- Radiology, Nuclear Medicine & Medical Imaging