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Accepted (AM)Open Access (License Unspecified), Open
Journal article
Fine particulate air pollution and premature atrial contractions: The REasons for Geographic And Racial Differences in Stroke study
Journal of exposure science & environmental epidemiology, v 27(3), pp 271-275
01 May 2017
PMID: 27649843
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Several reports have suggested that particulate matter (PM) exposure increases the risk for atrial arrhythmias. However, data from large-scale epidemiologic studies supporting this hypothesis are lacking. We examined the association of PM <2.5 mu m in diameter (PM2.5) concentration with premature atrial contractions (PACs) in 26,609 (mean age=65 +/- 9.4 years; 55% female; 41% black) participants from the REGARDS (REasons for Geographic And Racial Differences in Stroke) study. Estimates of short-(2 weeks) and long-term (1 year) PM2.5 exposure were computed before each participant's baseline visit using geographic information system data on the individual level at the coordinates of study participants' residences. PACs were identified from baseline electrocardiograms. A total of 2140 (8.2%) participants had evidence of PACs on the baseline electrocardiogram. Short-term PM2.5 (per 10 mu g/m(3)) exposure was not associated with PACs (OR = 1.09, 95% CI = 0.98, 1.23). Increases in long-term PM2.5 (per 10 mu g/m(3)) were associated with PACs (OR = 1.40, 95% CI = 1.10, 1.78). Interactions were not detected for short- and long-term PM2.5 exposure by age, sex, or race. Long-but not short- term PM2.5 exposure is associated with PACs. This suggests a role for long-term PM2.5 exposure in initiating supraventricular arrhythmias that are triggered by PACs.
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Details
- Title
- Fine particulate air pollution and premature atrial contractions: The REasons for Geographic And Racial Differences in Stroke study
- Creators
- Wesley T. O'Neal - Emory UniversityElsayed Z. Soliman - Wake Forest UniversityJimmy T. Efird - East Carolina UniversitySuzanne E. Judd - University of Alabama at BirminghamVirginia J. Howard - University of Alabama at BirminghamGeorge Howard - University of Alabama at BirminghamLeslie A. McClure - Drexel University
- Publication Details
- Journal of exposure science & environmental epidemiology, v 27(3), pp 271-275
- Publisher
- Springer Nature
- Number of pages
- 5
- Grant note
- F32HL134290 / NATIONAL HEART, LUNG, AND BLOOD INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI) U01 NS041588 / National Institute of Neurological Disorders and Stroke, National Institutes of Health, Department of Health and Human Service; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS) NASA Applied Sciences Program; National Aeronautics & Space Administration (NASA) U01NS041588 / NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics
- Web of Science ID
- WOS:000399843300005
- Scopus ID
- 2-s2.0-84988600941
- Other Identifier
- 991019168319604721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Environmental Sciences
- Public, Environmental & Occupational Health
- Toxicology