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Fine particulate air pollution and premature ventricular contractions: The REasons for Geographic And Racial Differences in Stroke (REGARDS) Study
Journal article   Open access   Peer reviewed

Fine particulate air pollution and premature ventricular contractions: The REasons for Geographic And Racial Differences in Stroke (REGARDS) Study

Wesley T. O'Neal, Elsayed Z. Soliman, Jimmy T. Efird, Virginia J. Howard, George Howard and Leslie A. McClure
Environmental research, v 154, pp 115-119
01 Apr 2017
DOI: https://doi.org/10.1016/j.envres.2016.12.031
PMID: 28061370
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://europepmc.org/articles/pmc5354125View
Accepted (AM)Open Access (License Unspecified),  Open

Abstract

Environmental Sciences Environmental Sciences & Ecology Life Sciences & Biomedicine Public, Environmental & Occupational Health Science & Technology
Background: It is unknown if higher levels of ambient particulate matter (PM) exposure increase the risk for premature ventricular contractions (PVC) in a population-based study of men and women, and if this relationship varies by race or sex. Methods: We examined the association of PM < 2.5 mu m in diameter (PM2.5) concentration with PVCs in 26,121 (mean age=64 +/- 9.3 years; 55% female; 41% black) participants from the REasons for Geographic And Racial Differences in Stroke (REGARDS) study. Estimates of short- (2-week) and long-term (1-year) PM2.5 exposures were computed prior to the baseline visit using geographic information system data on the individual level at the coordinates of study participants' residences. PVCs were identified from baseline electrocardiograms. Results: PVCs were detected in 1719 (6.6%) study participants. Short- (OR=1.08, 95%CI=1.03, 1.14) and long(OR=1.06, 95%CI=1.01, 1.12) term PM2.5 exposures were associated with PVCs. Interactions were not detected by race or sex. An interaction between short-term PM2.5 exposure and PVCs was detected for those with cardiovascular disease (OR=1.16, 95%CI=1.06, 1.27) compared with those without cardiovascular disease (OR=1.05, 95%CI=0.99, 1.12; p-interaction=0.027). Conclusion: Our findings suggest that PM2.5 exposure is associated with an increased risk for PVCs in a biracial population-based study of men and women. We also have identified persons with cardiovascular disease as an at-risk population for PVCs when increases in short-term PM2.5 concentration occur.

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7 citations in Web of Science
7 citations in Scopus

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UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being
#11 Sustainable Cities and Communities

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Collaboration types
Domestic collaboration
Web of Science research areas
Environmental Sciences
Public, Environmental & Occupational Health
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