Journal article
Flail mitral valve syndrome: Comparison with chronic mitral regurgitation of other etiologies
The American heart journal, v 109(3), pp 435-442
1985
PMID: 3976468
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Thirty-nine patients with symptomatic severe mitral regurgitation (MR) were studied by cardiac catheterization and two-dimensional echocardiography (2DE) prior to mitral valve replacement. A flail mitral valve was found at surgery in 23 patients (group 1); 16 patients had intact chordae tendineae (chronic MR, group 2). No difference was found between groups 1 and 2 with regard to hemodynamic findings. Left atrial volumes in end systole (LAESV) and end diastole (LAEDV) were determinod by 2DE from apical four- and two-chamber views with the use of a biplane area-length method and a light pen system. The LAESV and LAEDV measured 116 ± 66 ml and 56 ± 48 ml, respectively, in group 1, as compared with 185 ± 101 ml and 105 ± 62 ml in group 2 (
p < 0.025). Ten patients from group 1 with LAESV ≤ 100 ml (group 1A) were compared to the remaining 13 patients with LAESV > 100 ml (group 1B). Patients in group 1A had significantly smaller left ventricular volume and higher mean pulmonary wedge pressure, pulmonary artery, and left ventricular end-diastolic pressure compared to patients in groups 1B and 2 (
p < 0.05). Thus, a subset group of patients with flail mitral leaflets and smaller LAESV has hemodynamic features of acute MR, whereas the remainder with larger LAESV are indistinguishable from patients with chronic MR.
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Details
- Title
- Flail mitral valve syndrome: Comparison with chronic mitral regurgitation of other etiologies
- Creators
- Jian-Fang Ren - Hahnemann University HospitalIoannis P. Panidis - Hahnemann University HospitalMorris N. Kotler - Hahnemann University HospitalGary S. Mintz - Hahnemann University HospitalInder Goel - Hahnemann University HospitalJohn Ross - Hahnemann University HospitalJulia C Ross - Richard C. Goodwin College of Professional Studies (2001-)
- Publication Details
- The American heart journal, v 109(3), pp 435-442
- Publisher
- Mosby, Inc
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Richard C. Goodwin College of Professional Studies
- Web of Science ID
- WOS:A1985ADM0200002
- Scopus ID
- 2-s2.0-0022222165
- Other Identifier
- 991019184093204721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Cardiac & Cardiovascular Systems