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Flow-pressure drop measurement and calculation in a tapered femoral artery of a dog
Journal article   Peer reviewed

Flow-pressure drop measurement and calculation in a tapered femoral artery of a dog

R.K Banerjee, L.H Back and Y.I Cho
Biorheology (Oxford), v 32(6), pp 655-684
1995
PMID: 8857355

Abstract

In vivo shear rate non-Newtonian viscosity pressure drop shear stress velocity profile
This study describes the in vivo measurement of pressure drop and flow during the cardiac cycle in the femoral artery of a dog, and the computer simulation of the experiment based on the use of the measured flow, vessel dimensions and blood viscosity. In view of the experimental uncertainty in obtaining the accurate velocity profile at the wall region, the velocity pulse at the center was measured and numerical calculations were performed for the center Une instantaneous velocity and within the two limits of spatial distribution of inlet flow conditions: uniform and parabolic. Temporal and spatial variations of flow parameters, i.e., velocity profile, shear rate, non-Newtonian viscosity, wall shear stress, and pressure drop were calculated. There existed both positive and negative shear rates during a pulse cycle, i.e., the arterial wall experiences zero shear three times during a cardiac cycle. For the parabolic inlet condition, the taper of the artery not only increased the magnitude of the positive and negative shear rates, but caused a steep gradient in shear rate, a phenomenon which in turn affects wall shear stress and pressure. In contrast, for the uniform inlet condition, the flow through the tapered artery was predominantly the developing type, which resulted in reduction in magnitude of wall shear rate along the axial direction.

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6 citations in Scopus

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Collaboration types
Domestic collaboration
Web of Science research areas
Biophysics
Engineering, Biomedical
Hematology
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