Journal article
Focal Hepatic Glycogenosis in a Patient With Uncontrolled Diabetes Mellitus Type 1
Journal of computer assisted tomography, v 42(2), pp 230-235
01 Mar 2018
PMID: 28937487
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Hepatomegaly and elevated liver enzymes in patients with diabetes are commonly associated with fatty liver disease. However, physicians often forget about another intrinsic substance that can cause a similar clinical pictureglycogen. Liver stores approximately one third of the total body glycogen and is responsible for blood glucose homeostasis. Excessive hepatocellular glycogen accumulation occurs not only in congenital glycogen storage diseases, but also in acquired conditions associated with hyperglycemic-hyperinsulinemic states such as uncontrolled diabetes mellitus, high-dose corticosteroid use, and dumping syndrome. All reported cases of acquired abnormal glycogen deposition described a diffuse form of hepatic glycogenosis with the entire liver involved in the accumulating process. To our knowledge, this is the first reported case of abnormal focal glycogen deposition in a patient with diabetes mellitus type 1 with imaging and pathologic correlation. Awareness of the imaging appearance of focal glycogen deposition can help to distinguish it from other pathologic conditions.
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Details
- Title
- Focal Hepatic Glycogenosis in a Patient With Uncontrolled Diabetes Mellitus Type 1
- Creators
- Tetiana Glushko - Mercy Health SystemSergiy V. Kushchayev - Mercy Health SystemDmitry Trifanov - Mercy Health SystemAliaksei Salei - Mercy Health SystemDiego Morales - Drexel UniversityGerard Berry - Mercy Health SystemJustin Mackey - Mercy Health SystemOleg M. Teytelboym - Mercy Health System
- Publication Details
- Journal of computer assisted tomography, v 42(2), pp 230-235
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 6
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Medicine (Graduate)
- Web of Science ID
- WOS:000428221900010
- Scopus ID
- 2-s2.0-85044423236
- Other Identifier
- 991019168385404721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Radiology, Nuclear Medicine & Medical Imaging