Journal article
Fractionated CO2 Laser as Therapy in Recalcitrant Lichen Sclerosus
Journal of lower genital tract disease, v 24(2), pp 225-228
01 Apr 2020
PMID: 32068618
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Objectives
The aim of this study was to evaluate the efficacy of the fractionated CO2 laser in treating recalcitrant lichen sclerosus (LS). Materials and Methods
The study population was 40 women diagnosed with LS who were symptomatic despite medical treatment. Patients had at least 2 or more laser sessions with a 2-month follow-up visit at the Drexel Vaginitis Center. A fractionated CO2 laser was used on affected areas at mild or standard power settings. Analyses were performed of changes in symptom rating scales, verbal reports, and physical examination findings. Results
In the LS cohort of 40 patients, 22 women (55%) experienced symptoms that had persisted longer than 5 years before treatment. After the appropriate laser sessions, 72.5% of women described their improvement as significant or more than 66% improvement. In addition, there was a statistically significant reduction in vaginal pain, itching, dyspareunia, and dysuria. The presence of white epithelium decreased 20% after treatment. Furthermore, the mean corticosteroid use declined from 4.28 times per week to 2.04 times per week, indicating a resolution of many symptoms. Conclusions
The fractionated CO2 laser may be a helpful approach for managing LS that is unresponsive to traditional treatment options.
Metrics
Details
- Title
- Fractionated CO2 Laser as Therapy in Recalcitrant Lichen Sclerosus
- Creators
- Divya Balchander - Drexel UniversityPaul Nyirjesy - Drexel University
- Publication Details
- Journal of lower genital tract disease, v 24(2), pp 225-228
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 4
- Resource Type
- Journal article
- Language
- English
- Web of Science ID
- WOS:000524758000018
- Scopus ID
- 2-s2.0-85083041841
- Other Identifier
- 991019350600304721
UN Sustainable Development Goals (SDGs)
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Obstetrics & Gynecology