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Fractionated Stereotactic Radiotherapy for Facial Nerve Schwannomas
Journal article   Open access   Peer reviewed

Fractionated Stereotactic Radiotherapy for Facial Nerve Schwannomas

Wenyin Shi, Varsha Jain, Hyun Kim, Colin Champ, Gaurav Jain, Christopher Farrell, David W. Andrews, Kevin Judy, Haisong Liu, Gregory Artz, …
Journal of neurological surgery. Part B, Skull base, v 77(1), pp 75-80
01 Feb 2016
PMID: 26949592
url
https://europepmc.org/articles/pmc4777614View
Published, Version of Record (VoR)Open Access (License Unspecified) Open
url
https://doi.org/10.1055/s-0035-1564056View
Published, Version of Record (VoR) Open

Abstract

Original
Purpose  Data on the clinical course of irradiated facial nerve schwannomas (FNS) are lacking. We evaluated fractionated stereotactic radiotherapy (FSRT) for FNS. Methods  Eight consecutive patients with FNS treated at our institution between 1998 and 2011 were included. Patients were treated with FSRT to a median dose of 50.4 Gy (range: 46.8–54 Gy) in 1.8 or 2.0 Gy fractions. We report the radiographic response, symptom control, and toxicity associated with FSRT for FNS. Results  The median follow-up time was 43 months (range: 10–75 months). All patients presented with symptoms including pain, tinnitus, facial asymmetry, diplopia, and hearing loss. The median tumor volume was 1.57 cc. On the most recent follow-up imaging, five patients were noted to have stable tumor size; three patients had a net reduction in tumor volume. Additionally, six patients had improvement in clinical symptoms, one patient had stable clinical findings, and one patient had worsened House-Brackmann grade due to cystic degeneration. Conclusion  FSRT treatment of FNS results in excellent control of growth and symptoms with a small rate of radiation toxicity. Given the importance of maintaining facial nerve function, FSRT could be considered as a primary management modality for enlarging or symptomatic FNS.

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Collaboration types
Domestic collaboration
Web of Science research areas
Clinical Neurology
Surgery
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