Journal article
Frequency and predictors of concurrent complications in multi-suture release for syndromic craniosynostosis
Child's nervous system, v 40(1), pp 153-162
01 Jan 2024
PMID: 37462812
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Understanding the complication profile of craniosynostosis surgery is important, yet little is known about complication co-occurrence in syndromic children after multi-suture craniosynostosis surgery. We examined concurrent perioperative complications and predictive factors in this population.
In this retrospective cohort study, children with syndromic diagnoses and multi-suture involvement who underwent craniosynostosis surgery in 2012-2020 were identified from the National Surgical Quality Improvement Program-Pediatric database. The primary outcome was concurrent complications; factors associated with concurrent complications were identified. Correlations between complications and patient outcomes were assessed.
Among 5,848 children identified, 161 children (2.75%) had concurrent complications: 129 (2.21%) experienced two complications and 32 (0.55%) experienced ≥ 3. The most frequent complication was bleeding/transfusion (69.53%). The most common concurrent complications were transfusion/superficial infection (27.95%) and transfusion/deep incisional infection (13.04%) or transfusion/sepsis (13.04%). Two cardiac factors (major cardiac risk factors (odds ratio (OR) 3.50 [1.92-6.38]) and previous cardiac surgery (OR 4.87 [2.36-10.04])), two pulmonary factors (preoperative ventilator dependence (OR 3.27 [1.16-9.21]) and structural pulmonary/airway abnormalities (OR 2.89 [2.05-4.08])), and preoperative nutritional support (OR 4.05 [2.34-7.01]) were independently associated with concurrent complications. Children who received blood transfusion had higher odds of deep surgical site infection (OR 4.62 [1.08-19.73]; p = 0.04).
Our results indicate that several cardiac and pulmonary risk factors, along with preoperative nutritional support, were independently associated with concurrent complications but procedural factors were not. This information can help inform presurgical counseling and preoperative risk stratification in this population.
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Details
- Title
- Frequency and predictors of concurrent complications in multi-suture release for syndromic craniosynostosis
- Creators
- Sujay Rajkumar - Drexel University School of Medicine, Philadelphia, PA, USADaniel S Ikeda - Department of Neurosurgery, Walter Reed National Military Medical Center, Bethesda, MD, USAMichaela Scanlon - Department of Neurosurgery, Naval Medical Center San Diego, San Diego, CA, USAMargaret Shields - Department of Neurosurgery, Naval Medical Center San Diego, San Diego, CA, USAJohn R Kestle - Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, UT, USAJillian Plonsker - Department of Neurosurgery, University of California San Diego, San Diego, CA, USAMichael Brandel - Department of Neurosurgery, University of California San Diego, San Diego, CA, USADavid D Gonda - Division of Pediatric Neurosurgery, Rady Children's Hospital, San Diego, CA, USAMichael Levy - Division of Pediatric Neurosurgery, Rady Children's Hospital, San Diego, CA, USADonald J Lucas - Uniformed Services University of the Health SciencesPamela M Choi - Division of Pediatric Surgery, Department of General Surgery, Naval Medical Center San Diego, San Diego, CA, USAVijay M Ravindra - Division of Pediatric Neurosurgery, Rady Children's Hospital, San Diego, CA, USA. vijay.ravindra@hsc.utah.edu
- Publication Details
- Child's nervous system, v 40(1), pp 153-162
- Number of pages
- 10
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- College of Medicine
- Web of Science ID
- WOS:001031438800003
- Scopus ID
- 2-s2.0-85164984432
- Other Identifier
- 991021860617604721
UN Sustainable Development Goals (SDGs)
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Source: SDGs in the Output
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Clinical Neurology
- Pediatrics
- Surgery