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GE-Miner: integration of cluster ensemble and text mining for comprehensive gene expression analysis
Journal article   Peer reviewed

GE-Miner: integration of cluster ensemble and text mining for comprehensive gene expression analysis

Xiaohua Hu
International journal of bioinformatics research and applications, v 2(3), pp 325-338
2006
PMID: 18048169

Abstract

Algorithms Cluster Analysis Computational Biology - methods Computers Database Management Systems Databases, Protein Gene Expression Gene Expression Profiling Information Storage and Retrieval Multigene Family Natural Language Processing Oligonucleotide Array Sequence Analysis Pattern Recognition, Automated Software
Generating high quality gene clusters and identifying the underlying biological mechanism of the gene clusters are the important goals of clustering gene expression analysis. Based on this consideration, we design and develop a unified system Gene Expression Miner (GE-Miner) by integrating cluster ensemble, text clustering and multidocument summarisation and provide an environment for comprehensive gene expression data analysis. Experimental results demonstrate that our systems can obtain high quality clusters and provide concise and informative textual summary for the gene clusters.

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