Gay and Bisexual Men's Strategies to Maintain Daily Adherence to Their HIV Pre-exposure Prophylaxis (PrEP) Medication: Results from a Qualitative Study
Christian Grov, Anthony W P Flynn, Alexa B D'Angelo, Javier Lopez-Rios, David W Pantalone, Ian W Holloway and Jeffrey T Parsons
Adult Bisexuality - psychology HIV Infections - prevention & control Homosexuality, Male - psychology Humans Interviews as Topic Male Pre-Exposure Prophylaxis Qualitative Research Sexual Behavior Treatment Adherence and Compliance Young Adult
Since FDA approval in 2012, HIV pre-exposure prophylaxis (PrEP) has been adopted by key populations, including gay and bisexual men (GBM), to reduce their HIV transmission risk. Given that PrEP is optimally effective when taken as prescribed, it is critical to understand the adherence strategies GBM use. We conducted one-on-one, semi-structured interviews with GBM taking PrEP in 2015-2016 (n = 103). Using thematic analysis, we identified six adherence strategies, with most participants (84.3%) utilizing multiple strategies to maintain adequate adherence: (1) integrating PrEP into part of a daily routine, (2) using a pillbox, (3) cognitive strategies/visual cues, (4) setting recurring smartphone alarms or reminders, (5) keeping medication on oneself at all times, and (6) partner or peer support for reminders and/or pill sharing. Overall, participants reported high PrEP adherence (M = 1.6 missed doses in the prior 30 days), though nearly all described missing at least one dose unintentionally in the past. Participants credited their high levels of adherence in part to the strategies they adopted. Providers working with GBM prescribed PrEP, especially patients reporting difficulties with adherence, might consider recommending any or all of the six strategies described in this study.
Gay and Bisexual Men's Strategies to Maintain Daily Adherence to Their HIV Pre-exposure Prophylaxis (PrEP) Medication: Results from a Qualitative Study
Creators
Christian Grov - The Graduate Center, CUNY
Anthony W P Flynn - University of Wisconsin–Madison
Alexa B D'Angelo - CUNY Institute for Implementation Science in Population Health (ISPH), New York, NY, USA
Javier Lopez-Rios - The Graduate Center, CUNY
David W Pantalone - University of Massachusetts Boston
Ian W Holloway - University of California, Los Angeles