Journal article
Gene expression analysis enriched
Drug discovery today, v 9(21), pp 913-914
2004
PMID: 15501723
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The use of DNA microarrays to identify genes that are upregulated or downregulated is a crucial component in the early phase of drug target development, optimization and clinical validation. It is well recognized that a significant change that is revealed by statistical methods, even if fitted to the experimental objectives, does not always unlock all the biologically significant changes that are related to disease or treatment. Novel approaches to enrich expression analysis by including information on pathways, biomedical literature or phenotype have therefore increased interest in this approach.
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Details
- Title
- Gene expression analysis enriched
- Creators
- Andres Kriete (Corresponding Author) - Drexel University
- Publication Details
- Drug discovery today, v 9(21), pp 913-914
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000224647700007
- Scopus ID
- 2-s2.0-6344261798
- Other Identifier
- 991014877774104721
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- Web of Science research areas
- Pharmacology & Pharmacy