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Genitourinary manifestations of Epstein-Barr virus infections
Journal article   Open access   Peer reviewed

Genitourinary manifestations of Epstein-Barr virus infections

Randi Leigh and Paul Nyirjesy
Current infectious disease reports, v 11(6), pp 449-456
01 Nov 2009
DOI: https://doi.org/10.1007/s11908-009-0065-8
PMID: 19857384
url
https://link.springer.com/content/pdf/10.1007/s11908-009-0065-8.pdfView
Published, Version of Record (VoR) Open
url
https://doi.org/10.1007/s11908-009-0065-8View
Published, Version of Record (VoR) Open

Abstract

Disease transmission Infectious diseases Pathology Urogenital system Viruses Women
Epstein-Barr virus (EBV) is best known as the organism responsible for the syndrome of acute infectious mononucleosis. Transmission of EBV most commonly occurs through oral secretions. EBV has also been isolated from the female genital tract, where its role is poorly understood. This article reviews the available literature and data regarding EBV in the female genital tract and discusses areas of consensus and controversy. The primary manifestation of EBV seems to be vulvar ulcers, which are underrecognized. Diagnosis relies on appropriate serologic testing. Management includes local care and may require pain and corticosteroid medications. Although EBV is present elsewhere in the female genital tract, its pathogenic role in the cervix, uterus, fallopian tubes, and ovaries is poorly understood. [PUBLICATION ABSTRACT]

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