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Published, Version of Record (VoR)CC BY-NC-ND V4.0, Open
Journal article
Genomics, microbiomics, proteomics, and Chock for metabolomics in bronchopulmonary dysplasia
Seminars in perinatology, v 42(7), pp 425-431
01 Nov 2018
PMID: 30487069
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Bronchopulmonary Dysplasia (BPD) is a disorder with a multifactorial etiology and highly variable clinical phenotype. Several traditional biomarkers have been identified, but due to the complex disease phenotype, these biomarkers have low predictive accuracy for BPD. In recent years, newer technologies have facilitated the in-depth and unbiased analysis of 'big data' in delineating the diagnosis, pathogenesis, and mechanisms of diseases. Novel systems-biology based 'omic' approaches, including but not limited to genomics, microbiomics, proteomics, and metabolomics may help define the multiple cellular and humoral interactions that regulate normal as well as abnormal lung development and response to injury that are the hallmarks of BPD. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license. (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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Details
- Title
- Genomics, microbiomics, proteomics, and Chock for metabolomics in bronchopulmonary dysplasia
- Creators
- Charitharth Vivek Lal - University of Alabama at BirminghamVineet Bhandari - Drexel UniversityNamasivayam Ambalavanan - University of Alabama at Birmingham
- Publication Details
- Seminars in perinatology, v 42(7), pp 425-431
- Publisher
- Elsevier
- Number of pages
- 7
- Grant note
- U01HL122626 / NATIONAL HEART, LUNG, AND BLOOD INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI) SDG-17SDG32720009; U01 HL122626; R01 HD067126; R01 HD066982; U10 HD34216 / National Institutes of Health (NIH); United States Department of Health & Human Services; National Institutes of Health (NIH) - USA R01HD067126 / EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pediatrics
- Web of Science ID
- WOS:000454379200004
- Scopus ID
- 2-s2.0-85055626411
- Other Identifier
- 991019167599704721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Obstetrics & Gynecology
- Pediatrics