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Accepted (AM)Open Access (License Unspecified), Open
Journal article
Glenoid Cartilage Mechanical Properties Decrease after Rotator Cuff Tears in a Rat Model
Journal of orthopaedic research, v 30(9), pp 1435-1439
09 Mar 2012
PMID: 22407524
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Rotator cuff repairs are commonly performed to reduce pain and restore function. Tears are also treated successfully without surgical intervention; however, the effect that a torn tendon has on the glenohumeral cartilage remains unknown. Clinically, a correlation between massive rotator cuff tears and glenohumeral arthritis has often been observed. This may be due to a disruption in the balance of forces at the shoulder, resulting in migration of the humeral head and subsequently, abnormal loading of the glenoid. Our lab previously demonstrated changes in ambulation and intact tendon mechanical properties following supraspinatus and infraspinatus rotator cuff tendon tears in a rat model. Therefore, the purpose of this study was to investigate the effects of supraspinatus and infraspinatus rotator cuff tears on the glenoid cartilage. Nine rats underwent unilateral detachment of the supraspinatus and infraspinatus tendons and were sacrificed after four weeks. Cartilage thickness significantly decreased in the antero-inferior region of injured shoulders. In addition, equilibrium elastic modulus significantly decreased in the center, antero-superior, antero-inferior, and superior regions. These results suggest that altered loading after rotator cuff injury may lead to damage to the joint with significant pain and dysfunction. Clinically, understanding the mechanical processes involved with joint damage will allow physicians to better advise patients.
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Details
- Title
- Glenoid Cartilage Mechanical Properties Decrease after Rotator Cuff Tears in a Rat Model
- Creators
- Katherine E. Reuther - University of PennsylvaniaJoseph J. Sarver - University of PennsylvaniaSusan M. Schultz - University of PennsylvaniaChang Soo Lee - University of PennsylvaniaChandra M. Sehgal - University of PennsylvaniaDavid L. Glaser - University of PennsylvaniaLouis J. Soslowsky - McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, University of Pennsylvania, 424 Stemmler Hall, 36th and Hamilton Walk, Philadelphia 19104, PA. T: 215‐818‐8653; F: 215‐573‐2133.
- Publication Details
- Journal of orthopaedic research, v 30(9), pp 1435-1439
- Publisher
- Wiley
- Grant note
- R01 AR056658-02 || AR / National Institute of Arthritis and Musculoskeletal and Skin Diseases : NIAMS P30 AR050950-04 || AR / National Institute of Arthritis and Musculoskeletal and Skin Diseases : NIAMS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000306311400012
- Scopus ID
- 2-s2.0-84863834512
- Other Identifier
- 991019176638504721
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Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Orthopedics