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Accepted (AM)Open Access (License Unspecified), Open
Journal article
Grafting polymer brushes by ATRP from functionalized poly(ether ether ketone) microparticles
Polymers for advanced technologies, v 32(10), pp 3948-3954
Oct 2021
PMID: 34924736
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Poly(ether ether ketone) (PEEK) is a semi-crystalline thermoplastic with excellent mechanical and chemical properties. PEEK exhibits a high degree of resistance to thermal, chemical, and bio-degradation. PEEK is used as a biomaterial in the field of orthopedic and dental implants; however, due to its intrinsic hydrophobicity and inert surface, PEEK does not effectively support bone growth. Therefore, new methods to modify PEEK's surface to improve osseointegration are key to next-generation polymer implant materials. Unfortunately, PEEK is a challenging material to both modify and subsequently characterize thus stymieing efforts to improve PEEK osseointegration. In this manuscript, we demonstrate how surface-initiated atom transfer radical polymerization can be used to modify novel PEEK microparticles (PMP). The hard core-soft shell microparticles were synthesized and characterized by dynamic light scattering, attenuated total reflection-infrared, X-ray photoelectron spectroscopy, and transmission electron microscopy, indicating the grafted materials increased solubility and stability in a range of solvents. The discovered surface grafted PMP can be used as compatibilizers for the polymer-tissue interface.
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Details
- Title
- Grafting polymer brushes by ATRP from functionalized poly(ether ether ketone) microparticles
- Creators
- Liye Fu - Carnegie Mellon UniversityHossein Jafari - Carnegie Mellon UniversityMichael Giessl - University of KonstanzSaigopalakrishna S. Yerneni - Carnegie Mellon UniversityMingkang Sun - Carnegie Mellon UniversityZongyu Wang - Carnegie Mellon UniversityTong Liu - Carnegie Mellon UniversityKriti Kapil - Carnegie Mellon UniversityBoyle C. Cheng - Allegheny Health NetworkAlexander Yu - Allegheny Health NetworkSaadyah E. Averick - Allegheny Health NetworkKrzysztof Matyjaszewski - Carnegie Mellon University
- Publication Details
- Polymers for advanced technologies, v 32(10), pp 3948-3954
- Publisher
- Wiley
- Number of pages
- 7
- Grant note
- R21 AR076525 / National Institute of Arthritis and Musculoskeletal and Skin Diseases; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Arthritis & Musculoskeletal & Skin Diseases (NIAMS) R01 DE020843 / NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA DMR 1501324 / National Science Foundation; National Science Foundation (NSF)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Surgery; Neurosurgery
- Web of Science ID
- WOS:000656501100001
- Scopus ID
- 2-s2.0-85107331513
- Other Identifier
- 991021930450704721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Polymer Science