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Growing and working with peripheral neurons
Journal article   Peer reviewed

Growing and working with peripheral neurons

Yan He and Peter W Baas
Methods in cell biology, v 71
2003
PMID: 12884684

Abstract

Equipment Contamination - prevention & control Dissection - methods Cell Culture Techniques - instrumentation Cells, Cultured - cytology Cells, Cultured - physiology Ganglia, Spinal - physiology Rats Neurons - cytology Ganglia, Spinal - cytology Superior Cervical Ganglion - cytology Cell Culture Techniques - methods Chick Embryo Superior Cervical Ganglion - physiology Animals Culture Media - pharmacology Growth Substances - pharmacology
Cultures of vertebrate peripheral neurons have been used to address a variety of issues related to the cell biology of the neuron. They are particularly amenable to experimental manipulations, such as microinjection, and can be cultured under a variety of different conditions designed to meet the needs of the particular experiment. This chapter focuses on cultures of rat sympathetic neurons from the superior cervical ganglia and on cultures of chick sensory neurons from the lumbosacral dorsal root ganglia. Information is provided on methods for dissection, preparation of culture dishes and substrates, composition of media, relevant growth factors, reduction of nonneuronal contamination, and maintenance of the cultures.

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Cell Biology
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