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Journal article
Harnessing Spinal Interneurons for Spinal Cord Repair
Neuroscience insights, v 17, pp 263310552211016-26331055221101607
Jan 2022
PMID: 35615115
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Interest in spinal interneurons (SpINs), their heterogeneity in the naive spinal cord and their varying responses to central nervous system injury or disease has been steadily increasing. Our recent review on this topic highlights the vast phenotypic heterogeneity of SpINs and the efforts being made to better identify and classify these neurons. As our understanding of SpIN phenotype, connectivity, and neuroplastic capacity continues to expand, new therapeutic targets are being revealed and novel treatment approaches developed to harness their potential. Here, we expand on that initial discussion and highlight how SpINs can be used to develop advanced, targeted cellular therapies and personalized medicines.
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Details
- Title
- Harnessing Spinal Interneurons for Spinal Cord Repair
- Creators
- Lyandysha V Zholudeva - Gladstone InstitutesMichael A Lane - Drexel University
- Publication Details
- Neuroscience insights, v 17, pp 263310552211016-26331055221101607
- Publisher
- Sage
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Neurobiology and Anatomy
- Web of Science ID
- WOS:000800370400001
- Scopus ID
- 2-s2.0-85130755723
- Other Identifier
- 991019169635104721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Neurosciences