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Headache in multiple sclerosis: features and implications for disease management
Journal article   Open access   Peer reviewed

Headache in multiple sclerosis: features and implications for disease management

David Tabby, Muhammad Hassan Majeed, Branden Youngman and Jessica Wilcox
International journal of MS care, v 15(2)
2013
PMID: 24453766
url
https://doi.org/10.7224/1537-2073.2012-035View
Published, Version of Record (VoR)Open Access (License Unspecified) Open

Abstract

The aim of this study was to investigate the variables affecting headache occurrence in patients with multiple sclerosis (MS). Seventy-two MS patients with comorbid headaches completed a 28-item questionnaire. This evaluation assessed each patient's demographics, headache description and modifying factors, social history, and impact on quality of life. Our patients reported a wide spectrum of headache presentations, characteristics, and resulting disability. We discuss the patterns in our data in the context of current hypotheses regarding headache and MS causality. In our patients, migraines with aura strongly correlated with MS exacerbations, suggesting that they might be useful as a marker for flare-up onset. Patients' pain descriptions varied based on their headache frequency, history, and relationship to MS progression. Due to the severity of headache in MS patients and resulting impact on their activities of daily living, a thorough analysis of headache presentation is warranted in such patients.

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