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Accepted (AM)Open Access (License Unspecified), Open
Journal article
Health disparities are important determinants of outcome for children with solid tumor malignancies
Journal of pediatric surgery, v 50(1), pp 161-166
01 Jan 2015
PMID: 25598116
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The purpose of this study was to identify health disparities in children with non-CNS solid tumor malignancies and examine their impact on disease presentation and outcome.
We examined the records of all children (age≤18years) diagnosed with a non-CNS solid tumor malignancy and enrolled in the Texas Cancer Registry between 1995 and 2009 (n=4603). The primary outcome measures were disease stage and overall survival (OS). Covariates included gender, age, race/ethnicity, year of diagnosis, socioeconomic status (SES), and driving distance to the nearest pediatric cancer treatment facility. Statistical analyses included life table methods, logistic, and Cox regression. Statistical significance was defined as p<0.05.
Children with advanced-stage disease were more likely to be male, <10years old, and Hispanic or non-Hispanic Blacks (all p<0.05). Distance to treatment and SES did not impact stage of disease at presentation. However, Hispanic and non-Hispanic Blacks and patients in the lowest SES quartile had the worst 1- and 5-year survival (all p<0.05). The adjusted OS differed by age, race, and stage, but not SES or distance to the nearest treatment facility.
Race/ethnicity plays an important role in survival for children with non-CNS solid tumor malignancies. Future work should better define these differences to establish mechanisms to decrease their impact.
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Details
- Title
- Health disparities are important determinants of outcome for children with solid tumor malignancies
- Creators
- Mary T. Austin - The University of Texas MD Anderson Cancer CenterHoang Nguyen - The University of Texas MD Anderson Cancer CenterJan M. Eberth - University of South CarolinaYuchia Chang - Department of Health Services Research, The University of Texas M.D. Anderson Cancer Center, Houston, TexasAndras Heczey - Baylor College of MedicineDennis P. Hughes - The University of Texas MD Anderson Cancer CenterKevin P. Lally - Department of Pediatric Surgery, The University of Texas Medical School at Houston, Houston, TexasLinda S. Elting - The University of Texas MD Anderson Cancer Center
- Publication Details
- Journal of pediatric surgery, v 50(1), pp 161-166
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Health Management and Policy
- Web of Science ID
- WOS:000348043500035
- Scopus ID
- 2-s2.0-84922515846
- Other Identifier
- 991021855278904721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Pediatrics
- Surgery