Journal article
Hemophagocytic Lymphohistiocytosis and Pancreatic Cancer: A Rare Association
Journal of community hospital internal medicine perspectives, v 13(5), pp 68-71
02 Sep 2023
PMID: 37868670
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
A marrow biopsy couldn't be pursued as the patient died within a week of hospitalization. An autopsy was not per-formed as per family's request. Conclusion: HLH can occur secondary to solid cell malignancies including those from the pancreas and should be kept high in the differential in critically ill cancer patients who are nonresponsive to antibiotics. H-score has been reported to be a more sensitive tool compared to the HLH protocol, especially if used earlier during the presentation. Further research is needed to compare diagnostic efficacy for HLH protocol verses H-score especially in critically ill patients as they might benefit from steroid trial. A marrow biopsy couldn't be pursued as the patient died within a week of hospitalization. An autopsy was not per-formed as per family's request.Conclusion: HLH can occur secondary to solid cell malignancies including those from the pancreas and should be kept high in the differential in critically ill cancer patients who are nonresponsive to antibiotics. H-score has been reported to be a more sensitive tool compared to the HLH protocol, especially if used earlier during the presentation. Further research is needed to compare diagnostic efficacy for HLH protocol verses H-score especially in critically ill patients as they might benefit from steroid trial.
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Details
- Title
- Hemophagocytic Lymphohistiocytosis and Pancreatic Cancer: A Rare Association
- Creators
- Ali Jaan - Rochester General HospitalFarhan Khalid - Monmouth Medical CenterAbdullah M. Firoze Ahmed - College Station Medical CenterAhmed Salman - Rochester General HospitalTrisha Meghal - Monmouth Medical CenterDoantrang Du - Monmouth Medical Center
- Publication Details
- Journal of community hospital internal medicine perspectives, v 13(5), pp 68-71
- Publisher
- DIGITAL COMMONS BEPRESS
- Number of pages
- 6
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pediatrics
- Web of Science ID
- WOS:001104683300008
- Other Identifier
- 991021930441704721
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InCites Highlights
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- Web of Science research areas
- Hematology